AGTR1 1166A>C Reference Standard
CBPA0138
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| Introduction | |
| Format | Genomic DNA |
| Description | G-protein-coupled receptors (GPCRs) are the largest family of transmembrane proteins in humans, and these receptors serve as important regulators of almost every aspect of human physiology. The angiotensin II type 1 receptor (AT1R) is a prototypical GPCR best known for its central role in maintaining cardiovascular and renal homeostasis. Binding of the AT1R’s endogenous agonist, the eight-residue peptide angiotensin II (AngII), triggers AT1R activation of the heterotrimeric G protein Gq, which in turn activates calcium signaling that culminates in vasoconstriction. |
| Technical Data | |
| Gene | AGTR1 |
| AA Change | N/A |
| DNA Change | NM_000685.5:c.*86A>C |
| Chr position (GRCh37) | chr3:148459988 A>C |
| Allelic Frequency | 50% |
| Zygosity | Heterozygous |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8°C |
| Expiry | 36 months from the date of manufacture |
