EZR-ROS1/BaF3
CBP73324
询 价
留 言
产品描述
产品数据库
| I. Introduction | |||
|
Cell Line Name： |
EZR-ROS1/BaF3 |
||
|
Host Cell: |
Ba/F3 |
||
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) | ||
|
Application: |
Anti-proliferation assay and PD assay |
||
|
Freeze Medium: |
90% FBS+10% DMSO |
||
|
Complete Culture Medium: |
RPMI-1640+10%FBS |
||
|
Mycoplasma Status: |
Negative |
||
| II. Background | |||
| EZR, ezrin, is a member of the ERM family that links the cytoplasm to the actin cytoskeleton and regulates polarization and migration in leukocytes and macrophages. EZR plays a role in metastasis in a number of cancer types although decreased Ezr expression has been associated with decreased survival in clear cell renal carcinoma and an EZR-ROS1 fusion has been identified in lung cancer. | |||
| III. Representative Data | |||
|
1.Sanger of EZR-ROS1/BaF3 |
|||
|
2. Anti-proliferation assay Figure 2. CTG Proliferation Assay of BaF3 EZR-ROS1 (C5). |
|||
